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名稱	重組Human IL-2
型號(hào)
更新時(shí)間	2023-09-24
特點(diǎn)	IL-2是一個(gè)強(qiáng)大的免疫調(diào)節(jié)t細(xì)胞產(chǎn)生的淋巴因子抗原或促有絲分裂的刺激的反應(yīng)。IL-2 / IL-2R信號(hào)需要t細(xì)胞增殖和其他基本功能至關(guān)重要的免疫反應(yīng)。白IL-2刺激增長(zhǎng)和分化,NK細(xì)胞,淋巴因子激活的殺傷細(xì)胞,單核細(xì)胞、巨噬細(xì)胞和少突膠質(zhì)細(xì)胞。重組人類IL-2 15.5 kDa蛋白質(zhì),含134個(gè)氨基酸殘基,使用所有無動(dòng)物生產(chǎn)試劑。}

詳細(xì)內(nèi)容

一.產(chǎn)品名稱:Recombinant Human IL-2/重組Human IL-2

二.Catalog Number:AF-200-02

三.Synonyms:T-cell growth factor (TCGF), Aldesleukin

四.Description:

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond. Manufactured using all non-animal reagents.

五.AA Sequence:

MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK AKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT

六.Source:E.coli

七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

九.Cross Reactivity:

Bacteria, Cow, Dog, Human, Monkey, Mouse, Rat, Leech, Human + Mouse, Cow + Mouse